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GMP / Batch Manufacturing

Electronic batch record, materials and lots, lot genealogy, in-process controls, quality-unit release, deviations, and recall with timed mock exercises.

Materials & Lots

Know exactly what material is on site, what state it is in, and whether the quality unit has released it — so that nothing unreleased, expired or rejected can be dispensed into a batch.

Standards: ICH Q7 §6.3, §7.1–7.5; 21 CFR 211.84, 211.142; Schedule M Part I
What it includes (7 capabilities)
  • Material master: raw, packaging, intermediate, finished product
  • Shelf life, retest period, storage conditions and specification link
  • Hazard, allergen, sensitiser and controlled-substance attributes
  • Goods receipt against a supplier with COA capture
  • Lot register with quarantine, released, rejected, on-hold and consumed states
  • Quality-unit release or rejection of every received lot
  • FEFO issue and lot balance tracking

Batch Manufacturing Records

Produce a complete, contemporaneous, attributable record of how one batch was actually made — the materials and lots consumed, the equipment used, who performed and who checked each critical step, every in-process result against its limit, and the quality unit's release decision.

Standards: ICH Q7 §6.4–6.7, §8; 21 CFR 211.186, 211.188, 211.192; 21 CFR Part 11; Schedule M Part I
What it includes (10 capabilities)
  • Master Batch Record with revisions, approval and immutability once effective
  • Bill of materials with overage and critical-dispensing flags
  • Process steps with equipment, durations and line clearance
  • In-process controls with enforced numeric limits
  • Batch execution against the pinned MBR revision
  • Material dispensing with lot genealogy and second-person verification
  • In-process results judged against the limit in force at the time
  • Yield reconciliation against the approved range
  • Quality-unit batch record review and release, with electronic signature
  • Printable batch manufacturing record and genealogy trace

Deviations

Capture every departure from the approved instruction as a record in its own right, assess its impact on the batch it affected, and stop that batch being released until the deviation is closed.

Standards: ICH Q7 §2.16–2.18, §6.7; 21 CFR 211.192; Schedule M Part I
What it includes (6 capabilities)
  • Planned and unplanned deviations raised against a batch, step or lot
  • Immediate action and containment
  • Quality-unit impact assessment on the affected batch
  • Batch hold and release, exercisable independently of the deviation
  • Disposition with justification
  • Escalation into the existing RCA and CAPA engine

Recall & Traceability

Find every affected lot and every consignee holding it within the time a scheme or a regulator expects, prove recovery against a target, and rehearse the whole thing with a timed mock recall.

Standards: ICH Q7 §10.2, §15; 21 CFR 117.139; Codex CXC 1-1969 §7; FSSAI (Food Recall) Regulations 2017; ISO 22000 §8.9.5
What it includes (7 capabilities)
  • Despatch register: which lot went to which consignee, and when
  • Recall, market withdrawal and mock recall exercises in one record
  • Affected lots resolved automatically by walking the genealogy chain
  • Measured traceability time — the number a GFSI auditor asks for
  • Consignee notification list built from despatch records, with responses
  • Recovery reconciliation against a stated effectiveness target
  • Regulator and public-notification tracking

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